Thrombopoietin: tickling the HSC's fancy

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Thrombopoietin: tickling the HSC's fancy

Thrombopoietin (THPO) has been well characterized as a key regulator of platelet production. THPO also plays an important role in the maintenance and regulation of hematopoietic stem cells (HSCs). In this issue of EMBO Molecular Medicine, Pecci et al (2018) describe a newly identified homozygous mutation in THPO causing congenital amegakaryocytic thrombocytopenia, a disease characterized by a s...

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ژورنال

عنوان ژورنال: EMBO Molecular Medicine

سال: 2017

ISSN: 1757-4676,1757-4684

DOI: 10.15252/emmm.201708450